@Meg's post in the other thread got me thinking about my old Nero sequel pitches.
I thought Fortuna was his strongest asset as a character. Leaning into his relationship with the city and its traditions would set him more apart from Dante. Plus apparently he was ostracized as a kid and really only interested in the Order for Kyrie. So I would've explored that more if I had to adapt 4 and I'd try to those those traits back in a sequel. Setting it in Fortuna is a way to do both.
I thought Nero was better as a team player than a lone wolf. So I'd have a game where Nero works with two or three new characters in order to defeat a shared threat.
@ef9dante_oSsshea asked about Nero having a twin. It could be cliche but twins do run in families. I have a fraternal twin sister and i have triplet aunts. So i'd give Nero a fraternal twin sister and explore his mother's side of the family. His mother was a Witch who traveled with Vergil. She was forced to give Nero up so she left him in Fortuna while she fled from an unknown enemy. I'm retconning the novel that stated Vergil left him there but 5 made it seem like he didn't know Nero existed so this feels smoother.
There was a post about killing Kyrie off but I'd subvert that cliche by bringing her back as a ghost. It's inspired by the British show Being Human. The plot is less about avenging her but finding out whether she could be brought back to life fully. The rival is another couple who wants to do the same but they are less concerned about morality.
I had fairytale pitches for Dante and Vergil- the Wizard of Oz and Momotaro respectively. So I'd do one for Nero too. All 3 would focus on an adventure they had in their childhood that has consequences in the modern day.
A way to do a remake of 1-3 without actually remaking the game is to have Nero do another case in the same setting. Its similar to Doctor Who or Star Wars as settings will get revisited with new stories.
My problems with Nero are just a bad first impression. So this is a more manageable way to fix him and showcase what he brings to the table. At the end of the day his problems are just same as the legacy characters from Marvel or DC. So looking at them would be a good way to go.